tc-99m mercaptoacetyltriglycined (MAG3) is a new Tc-99m renal agent that is excreted by tubular function. To evaluate the efficacy of Tc-99m MAG37 renal scans with Tc-99m MAG3 and Tc-99m diethylenetriamine penta-acetic acid(DTPA) were performed
in
patients with upper urinary tract obstruction within the time interval of 3 dyas. Of the 36 patients 17 had ureteropelvic junction (UPJ0 strictures, 5 had renal stones, 10 had ureteral stones, and 4 had ureterovesical junction (UVJ) strictures.
The
patient ages were ranged from 1 to 72 years and the mumbers of male and female were 22 and 14, respectively. Split renal function ratio(%), time parameters and image quality using target to background ratio of the Tc-99m MAG3 renal scan were
ompared
with those of Tc-99m DTPA, in terms of age group (less than 16, 16 or more), obstruction site (UPJ or proximal to UPF, distal to UPJ) and treatment (pre-treatment, post-treatment state). The split renal function ratio(%) of Tc-99m MAG3 was well
correlated with that of Tc-99m DTPA (r=0.92). there was no statistically significant difference between time paramters of Tc-99m MAG3 and Tc-99m DTPA. The image quality of tc-99m MAG3 was superior to that of Tc-99m DTPA (p<0.05).
In conclusion, Tc-99m MAG3 renal scan had a superior image quality to that of Tc-99m DTPA and correlated well with other Tc-99m DTPA parameters. Thus, Tc-99m MAG3 renal scan may be considered to replace Tc-99m DTPA in the evaluation of patients
with
upper urinary tract obstruction.
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